梁鑫 博士

副教授

1999-2003 学士     上海交通大学
2003-2007 博士      上海交通大学
2008-2014 博士后     马普细胞生物学和遗传学研究所
2015-2019 马普国际伙伴小组组长  
2015-  助理教授、副教授 清华大学生命科学学院

●  研究兴趣、领域：

1. 细胞骨架动力学及其调控的分子机制
2. 果蝇基于细胞骨架的机械力信号转导的分子基础

●  开设的课程：

《生理学》，48学时，春季学期，本科生必修专业课

●  代表性论文：

1. Xie, S. *, J. Li, S. Sun, W. Chen, H. Cheng, Y. Song, Y. Li, M. Liu, X. Zhu, X. Liang*, and J. Zhou*. 2022. TUBright: A Peptide Probe for Imaging Microtubules. Anal Chem.

2. Diao, L., M.Y. Liu, Y.L. Song, X. Zhang, X. Liang*, and L. Bao*. 2022. alpha1A and alpha1C form microtubules to display distinct properties mainly mediated by their C-terminal tails. J Mol Cell Biol. 13:864-875.

3. Shree, S., S. Sutradhar, O. Trottier, Y. Tu, X. Liang, and J. Howard*. 2022. Dynamic instability of dendrite tips generates the highly branched morphologies of sensory neurons. Sci Adv. 8:eabn0080.

4. Sun, L., L. Cui, Z. Liu, Q. Wang, Z. Xue, M. Wu, T. Sun, D. Mao, J. Ni, J.C. Pastor-Pareja, and X. Liang*. 2021. Katanin p60-like 1 sculpts the cytoskeleton in mechanosensory cilia. J Cell Biol. 220.

5. Liao, M., X. Liang, and J. Howard. 2021. The narrowing of dendrite branches across nodes follows a well-defined scaling law. Proc Natl Acad Sci U S A. 118.

6. Li, S., K.Y. Wan, W. Chen, H. Tao, X. Liang*, and J. Pan*. 2020. Functional exploration of heterotrimeric kinesin-II in IFT and ciliary length control in Chlamydomonas. Elife. 9.

7. Song, Y., Y. Zhang, Y. Pan, J. He, Y. Wang, W. Chen, J. Guo, H. Deng, Y. Xue, X. Fang, and X. Liang*. 2020. The microtubule end-binding affinity of EB1 is enhanced by a dimeric organization that is susceptible to phosphorylation. J Cell Sci. 133.

8. Liang, X*. 2019. Microtubule nucleation and dynamic instability in interphase fission yeast. J Mol Cell Biol. 11:941-943.

9. Sun, L., Y. Gao, J. He, L. Cui, J. Meissner, J.M. Verbavatz, B. Li, X. Feng, and X. Liang*. 2019a. Ultrastructural organization of NompC in the mechanoreceptive organelle of Drosophila campaniform mechanoreceptors. Proc Natl Acad Sci U S A. 116:7343-7352.

10. Sun, T., Y. Song, J. Dai, D. Mao, M. Ma, J.Q. Ni, X. Liang, and J.C. Pastor-Pareja*. 2019b. Spectraplakin Shot Maintains Perinuclear Microtubule Organization in Drosophila Polyploid Cells. Dev Cell. 49:731-747 e737.

●  荣誉、奖励及参加学术团体的情况：

2015-               马普伙伴小组奖励计划   

●  联系方式：

邮件：xinliang@tsinghua.edu.cn
Orcid ID: https://orcid.org/0000-0001-7915-8094/print